background image

袁云显萋塞墓丕丝盥缝鲞垄室蕉土超痘瘗童趁瑟塑渔症生丝缝攫墓!垒翅

富颈环形电切术在宫颈上皮内瘤变诊断和治疗中的作用

南云泽金延泽郑

喜延边大学医院妇产科(吉林延吉)

133000

・1881・

・妇女保健・

中国豳书分类号RTI&4

文献标识码A

文章编謦1001-4411{2007}14-1881-03

【摘要】

目的:探讨寓颈环形电切术(LEEP)在官颈上皮内瘤变诊断和治疗中的作用。方法:2003年2月一2004年12

冀采属LEEP对拍搠经过缨憨学、羽道镜下害颈多点添捡病理诊瞬CIN.病人进行遂一步诊凝翻治疗,对其疗效、术后劳发疲俸

回顾性分析。结果;46例年龄为2l一52多,平均3s。o辛岁,30一39岁26例,占56.52%;朝鲜族24侧,汉族22例,两组糖

比,无照著性差异(P>O.01)。细胞学检焱正常2例(4.34%),不典型鳞状上皮(ASCAS)9例(19.57%),低度鳞状上戍内

痍变(LSIL)24例(52。17%),高度鳞状上皮内病变<HSIL)11例(23。91%)。阴道镜下宫颈多点活检病理诊断为CIN

l 26

例、CIN嚣15铡、CINIII 5攒。零后病理诊断与术前完全符合者筠德,占稻.48%,零后瘸理缓裂下降15镶,蠢32.6%,零后

病理级别上升ll例,占23.9l%。2例术前诊断为CIN m,术后病理为宫颈鳞状上皮浸润癌而行宫颈癌根治术。随访中44例

(除外2例因宫颈漫润癌行宫颈癌根治术)细胞学均正常,2例术膀标本宫颈管处切缘CINm病变阳性,1个月聪行宫颈冷刀锥

锈术。LEEP治愈率为91。3%(42/46)。维论:LEEP怒诊治CIN鳇安全有效方法,哥浚弥褥酲遘镜下活检的嚣限往,哭要攀握

手术指征,规范手术步骤,切照宫颈管组织,术后密切观察,可获得满意的疗效。

【关键词】

嚣颈环形电切术宫颈上皮内瘤变病理诊断

The effect of loop electrosurgical exicision procedure

on

diagnosis and

treatment

for

cervical intraepithelial neoplasia

NAN

Yun—ze。】l鹣Yan—Ze,ZHENG羝,Department of

Obstetrics and

Gynecology,Affiliated

Hospital

of

Yanbian Uni—

versity,YanJi

33000,五lin,China

(Abstract】

Objective:To

study the effect of loop

electrosurgical

excision

procedure(LEEP)锄diagnosis

and treatment for cervi-

cal intraepithelial

neoplagia(CIN).Methods:46

cases

wi掇CIN

identified by cytology

and

pathological biopsy under

colposcopy treated

by

LEEP from

February

2003

to

December 2004,were analyzed retrospectively.Results:The ages of the 46

Cl/18eS

were

21

to

52 years old

(the

average

age

wag

38.04),in

which 26

cas档were

30 to 39.There

Wag

no

significant difference of

nationalities

between

Korean(24

ca-

s黯)and

Chinese(22cages).Normal

cytology襁2

CaStrO(4.强%),ASCA。S

Wag

es.ses(19.露%≥,LSIL

W8824㈣≤52.17%),

HSIL

WaS

11

c螂(23,91‘%).26

ca8es

of CIN l,15

case!s

of CIN II,5

caBe8

of CIN III,all

of

which diagnosed

by pathological

biopsy

under

eolpescopy.The

postoperative diagnosis ot"20

eases(43.48%)were

in

accordance

with the

preoperative ones.The

postoperative diag-

nosis were

downgraded in 15

cases(32。6%)and

upgraded

in 11

cas髂(23.91%>,2

Cases being diagnosed躐CIN珏before

operation,

whose

postoperative

pathological

diagnosis were squamous cell carcinoma of cervix

accepted radical

hysterectomy.Postoperative bleeding

in

15cages,lower

abdominal

pain

in

5cases,vaginal

discharge in 36 ca8e‰44

c船es(excluding

cases

of

wglamoas

cell carcinoma who

ac;,

cepted radical

hysterectomy)were

showed

110

abnormalities

in Pap smear during follow—up,while

2 cages

among them

demonstrated

H施-

hie resection

margin

and

give.the

Cold Knife

Conization(CKC)after

one

month‘.The CUre

rate was

91.3%(42/46).33

Cage8

were

fol-

lowed

for

one

year

and 1l

c88e8

for

half

year

to

one

year after

operation.Conclusion:LEEP

is

safe

and effective

procedure in treating

CIN.Satisfactory results

Call

be achieved

by mastering

surgical

indication and

standard

procedure,excising

cervical

canal

sufficiently and

paying

attention

to

postoperative

pathology.

[Key words]Loop

electrosurgical

excision

procedure(LEEP);Cervical

intraepithelial

neoplasia(CIN);Pathology

diagnosis

宫颈上皮态瘸变(cervical

intraepithelial

neoplasia,oN)

是宫颈没润癌演变发展过程中的癌前期瘸燮阶段,从CIN发

展为宫颈癌约需lO年,近年来年轻宫颈癌的发生率裔明显上

舞趋势,浚每年2强一3%的速度增长¨’,所浚对富颈瘸的醣

治重点在于对CIN的诊断与治疗上。近年来宫颈环行电切术

(100p

electrosurgieal excision

procedure,LEEP)广泛应用于

CIN的诊断和治疗。龌EP在去除病交酶弱瓣,又挺供了缝缓

病理学诊断。本文对2003年2月一2004年12月我院行LEEP

手术酶稻铡CIN病入瓣裰关资辩送行运籁牲努耩。

1资料与方法

1.1

一觳资瓣辐鲷年龄秀2l一52罗,警均3s.酣岁,

30—39岁者26例,占56.52%,>40岁者17例,占

36。96%;<30岁者3例,占6.5%;朝鲜族斛例,汉族22

铡,两缝耀爨:无显著豫差异(P>0。01>。全部穗有性搏侮,

有妊娠分娩史者43例。

 

万方数据