stage postoperative cervical carcinoma with high-risk factors.
Methods Seventy eight patients of early stage post operative
cervical carcinoma with high-risk factors were randomly divided into
two groups
, 40 cases received concurrent chemoradiotherapy and
38 cases received radiotherapy. Two groups received the same
radiotherapy. The concurrent chemoradiotherapy group were given
cisplatin when irradiated. Results The intrapelvic recurrence rate of
two groups were no significant difference. The extrapelvic
recurrence rate of the concurrent chemoradiotherapy group was
significant lower than the radiotherapy group.The 3-year survival
rates of radiotherapy group and concurrent chemoradiotherapy
group were 92.5
% and 76.3
% respectively.There were significant
difference between them. Only the gastrointestinal tract reaction
among the complication and adverse reaction in chemoradiotherapy
group were significant heavier than in radiotherapy group.
Conclusion The effect of concurrent chemoradiotherapy on early
stage postoperative cervical carcinoma with high-risk factors could
increase the survival rate of the patients. The adverse reaction of
two groups was no significant difference but gastrointestinal tract
reaction. The patients could tolerate. It is reasonable and effective
therapy.