异丙酚靶控输注联合气管表面麻醉在婴幼儿气管异物取出术中的应
用
【摘要】
目的 探讨异丙酚靶控输注联合咽喉、气管内表面麻醉应用于小儿气管支气
管异物取出术的疗效,并与氯胺酮复合 γ-
羟基丁酸钠麻醉比较。方法 40 例婴幼儿气管、
支气管异物病人,年龄 8~36 月,体重 7.5~18kg,随机分为 A 组和 B 组。A 组为异丙酚
效应室靶控输注联合 1%丁卡因咽喉、气管表面麻醉,B 组为氯胺酮复合 γ-羟基丁酸钠麻
醉,观察麻醉效果,并发症和苏醒时间。结果 2 组病人均麻醉成功,全部一次顺利插入
硬式支气管镜。B 组病人术中最低 SpO2 低于 A 组;支气管镜置入后发生较严重屏气、呛咳
需处理的病例 A 组为 1 例,B 组为 5 例。B 组术毕全部病例发生下颌松弛和舌后坠,显著
多于 A 组(1 例)(P<0.01)。术毕发生喉鸣、托下颌仍吸气困难 B 组 12 例,显著多于 A
组(0 例)。B 组病人术毕在手术室滞留时间、苏醒时间长于 A 组(P<0.01
)。结论 异丙酚
靶控输注联合气管表面麻醉是一种可控性强、安全、实用的婴幼儿气管支气管异物取出术
的麻醉方法。
【关键词】 二异丙酚;药物释放系统;表面麻醉;婴幼儿;气管;异物
Propofol Target Controlled Infusion Combined Trachea Topical Anaesthesia for
Tracheobronchial Foreign Body Removal in Children JIN Lie-lie, XU Xu-zhong, ZHANG
Xu-tong. Department of Anesthesiology, the First Affiliated Hospital of Wenzhou Medical
College, Wenzhou 325000, China
【Abstract】 Objective: To investigate the effect of propofol target controlled infusion(TCI)
combined throat and trachea topical anaesthesia for tracheobronchial foreign body removal in
children and compare it to ketamine combined sodium
作者单位:325027 温州市,温州医学院附属第一医院麻醉科(金烈烈、徐旭仲);
附属第二医院(张旭彤)
γ-hydroxybutrate anaesthesia. Methods: Forty patients, aged 8-36M , weighted 7.5-18kg and
scheduled to undergo tracheobronchial foreign body removal were randomly enrolled into two
groups: group A and group B. Propofol TCI combined throat and trachea topical anaesthesia with
1% decicaine in group A. Ketamine combined sodium γ-hydroxybutrate anaesthesia in group B.